Mekele is basically the gateway to the Danakil Depression. You don't really need to spend much time in Mekele as it's not really a toruist destination, but ended up spending a few days because of my poor planning. It's probably the nicest and most developed town in Ethiopia, with great food and a couple of moderately interesting sites. But don't go out of your way to visit unless you're passing through to the Danakil Depression or the Tigray Churches.
Read about Mek'ele on my blog →